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This is the amplification of pain transmission along the entire pain neuraxis, from peripheral nociceptors to the upper CNS regions that form the pain matrix and encode the perceptive, cognitive, and emotional aspects of pain [164]

This often includes athletes with sports-related injuries like muscle tears or tendonitis, people recovering from surgery, or those with soft tissue damage

Reduce exposure to toxins: choose low-VOC products, avoid BPA and phthalates in plastics, filter drinking water if contamination risk exists, and limit pesticide residue by washing produce

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