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Y. Xionget al., Neuroprotective and neurorestorative effects of thymosin 4 treatment following experimental traumatic brain injury, Wiley, Oct. 2012. doi: 10.1111/j.1749-6632.2012.06683.x

not shown) or electrophilic attack may be preceded by electronic excitation of NAPQI

Equally unresolved is how redox thresholds are established namely, when GSH-mediated buffering shifts from protective to permissive for cell death, and how changes in NADPH availability, metal speciation, or mitochondrial dependence reprogram this balance