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Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage

It plays a key role in energy metabolism by facilitating the transport of long-chain fatty acids into the mitochondriathe cells powerhouseswhere they are used to produce ATP

moreover, the heightened proliferation and turnover of leukocytes amplify its depletion, since these cells can concentrate vitamin C up to a hundredfold higher than plasma levels, ultimately leading to a substantial reduction in systemic vitamin C availability during sepsis (Oudemans-van Straaten et al., 2014