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However, its safety and effectiveness have not been established in large human clinical trials

In the forced swimming test a reduction of the immobility time in the NaBPC157 (10 g, 10 ng, 10 pg/kg, i.p.) treated rats corresponded to the activity of animals treated with 15 mg or 40 mg (i.p.) of the conventional antidepressants, imipramine or nialamide, respectively

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