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Table 11.6 Dietary Reference Intakes for Selenium Selenium at doses several thousand times the RDA can cause acute toxicity, and when ingested in gram quantities can be fatal

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In -synuclein-induced PD mouse model, Zhang and collaborators showed that the administration of caffeic acid prevents the neurodegeneration of dopaminergic neurons in SN and improves behavioral abnormalities by stimulating autophagy through the JNK/BcL2 pathway (Zhang et al., 2019)

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