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Contributing factors may include female age, anatomical and chromosomal irregularities, genetic predispositions, endocrinological issues, placental abnormalities, infections, lifestyle choices such as smoking and alcohol use, psychological influences, and exposure to environmental hazards like heavy metals, pollution, and radiation ( Despite ongoing research, the underlying causes of RM remain elusive, hindering effective treatment options and adding to the emotional burden on patients

Immunohistochemistry Seven-micrometer-thick cryosections were cut from the OCT-embedded biopsy specimen using a cryostat (Leica CM1950)

An association between variants in the IGF2 gene and BeckwithWiedemann syndrome: interaction between genotype and epigenotype