But most of the topical formulation contains Vitamin C derivatives and not the actual vitamin C
It is thought to produce an analgesic effect by reducing levels of pain mediators such as tumor necrosis factor-alpha, prostaglandins, interleukin 1-beta, and beta-endorphins, as well as by increasing local microcirculation
Afterward, most clients feel relaxed, refreshed, and hydrated
In addition to their anti-inflammatory effects, these compounds have inhibitory effects on the following pathways: inflammasome (NLRP3), Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway, endothelial cell vascular cell adhesion molecule-1 (VCAM-1) or intercellular adhesion molecule-1 (ICAM-1), matrix metalloproteinases involved in remodelling and metastasis (MMP 2, MMP 9), and chronic cycloxogenase derived prostaglandins that promote angiogenesis and immunosuppression (182)