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10.1080/21655979.2020.1860491 302 WehbeR.FrangiehJ.RimaM.El ObeidD.SabatierJ.-M.FajlounZ

Advanced purification techniques such as the heat-shock method, ammonium sulfate precipitation, gel filtration chromatography, ion exchange chromatography, and affinity chromatography are essential for maintaining its effectiveness and meeting the stringent purity standards required for clinical applications

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Peripheral arterial disease and critical limb ischemia represent potential applications based on BPC-157's pro-angiogenic effects and demonstrated improvements in blood flow recovery in hind limb ischemia models