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While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control
Some individuals, particularly those with MTHFR gene variants, convert cyanocobalamin poorly
B12 and Energy During Active Weight Loss on Tirzepatide Adequate B12 status directly supports mitochondrial energy production, the synthesis of red blood cells, and myelin formation in nervesall critical for sustaining the physical activity and mental clarity needed during weight loss
