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Concurrently, iron-mediated radical reactions further amplify oxidative stress, thereby lowering the cellular threshold for ferroptosis-related damage under conditions of sustained metabolic and redox perturbation [288,289,290]
In the puncture-only IVD group, collagen orientation within the AF was disrupted, whereas in the DFb-treated IVD groups, abundant type I and type II collagen fibers were observed
