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Although data on the long-term outcomes of patients with CD after infliximab withdrawal are limited, long-term follow-up results over 7 years from the STORI cohort showed that about one-fifth of the patients did not restart infliximab or another biologic agent, and this did not result in major complications

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This conclusion was reached via an integrated multi-omics approach, incorporating metabolomic and transcriptomic profiling, alongside validation in a lung epithelial-specific Cpt1a-deficient murine model and corroborating clinical data

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