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To determine whether VPA-induced synaptic changes were driven by pre- or post-synaptic alterations, we also examined VGLUT-1 and PSD-95 individually

Largest reductions (18-20%) occurred in the high-dose group after 1 and 2 weeks Combined dose groups significantly reduced the ratio by 14% after 1 and 2 weeks The decreases observed in oxidized:reduced GSH as a result of oral liposomal GSH supplementation are likely indicative of a general systemic reduction in oxidative stress levels. Plasma levels of 8-isoprostane (a marker of oxidative stress) decreased after liposomal glutathione supplementation

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[cited 10 Aug 2021]