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Talk to your doctor before starting if you: Are allergic to B12 Have optic nerve issues (optic atrophy) Have blood in urine or polycythemia Are pregnant, breastfeeding, or trying to conceive Have low iron or folate, or an active infection Dosage, Concentration, Route of Administration Dosage: Always follow the guidance of a licensed medical provider for the correct dosage

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These peripheral and central deficits can include severe gastrointestinal lesions, intracranial (superior sagittal sinus) hypertension, brain swelling and lesions, portal and caval hypertension, aortic hypotension, peripheral and central thrombosis, inferior caval vein and superior mesenteric vein congestion, azygos vein failure, electrocardiogram (ECG) disturbances, and heart, lung, liver, and kidney lesions (Vukojevic et al., 2018