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Curr Drug Saf 16:154164

The main clinical manifestation of AKI is the sudden or continuous decline of renal function in a short time (several hours to weeks), resulting in the accumulation of harmful and toxic metabolites in the body, and severe patients may also progress to renal failure or even death (Deep et al., 2021)

Statistics and reproducibility Infectivity assays were performed with eight repeats

designed an OoC device consisting of microfluidic channels with a flexible membrane, coated with ECM, where human intestinal cells (Caco-2) were seeded ( Figures 3D-F ) (123)