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reported that ISL alleviated liver fibrosis by triggering HSCs ferroptosis through the suppression of GPX4 and elevation of TfR and DMT1 expression, thereby generating a significant amount of ROS (Huang et al., 2022b)

168 Studies in experimental models have shown an association between AATD and oxidative stress

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Leading global healthcare company Novo Nordisk, who is a top contender for the industry's first $1trn valuation after the launch of its groundbreaking diabetes drug Ozempic in 2017, is set to introduce a promising new weight-loss treatment called CagriSema