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Mutations in the superoxide dismutase 1 gene encoding Cu/Zn-SOD were found in patients with familial ALS, resulting in excessive production of hydroxyl radicals and massive oxidative stress, resulting in ALS disease occurrence 44

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Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others References Anestal K, Prast-Nielsen S, Cenas N, Arner ES (2008) Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells

[DOI] [PubMed] [Google Scholar] 41.Petrovska B.B