gliotoxin and glutathione

gliotoxin and glutathione from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase: Cell Chemical Biology Evidence for Gliotoxin–Glutathione conjugate adducts

Name: gliotoxin and glutathione from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase: Cell Chemical Biology Evidence for Gliotoxin–Glutathione conjugate adducts
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10.31083/j.fbl2809209 39 HeckerL.ChengJ.ThannickalV

Using a long-term HFD-fed mouse model of NAFLD, we demonstrated in this study that NAFLD development occurs concomitantly with dysregulated hepatic glutathione homeostasis characterized by decreased GSH and increased GSSG, and increased TNF protein levels in both the circulation and the liver