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Consequences of this include oxidative damage to DNA, proteins and cell membrane lipids, and altered cellular signal transductions as observed in many disorders such as diabetes, cardiovascular, autoimmune and chronic kidney diseases [5]

As demonstrated in Figure 2, the most relevant abundant genera in the initial sediment were Izimaplasma (21.34%), Tangfeifania (15.65%), Halomonas (11.73%), Desulfotignum (9.28%), Guyparkeria (1.96%) and Sphaerochaeta (1.44%)

In the following part, we will describe the different vaccine-based strategies of senotherapeutics that have been studied, and we will show the limitations of some of them to be used into clinics

They act as signalling molecules to support recovery, metabolism, or growth-hormone pathways