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Embryos were incubated in E3 medium (5 mM NaCl, 0.17 mM KCl, 0.33 mM CaCl 2 , 0.33 mM MgSO 4 ) containing DMSO or ZIL from 1.5 to 24 hpf
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Figure 9 showed the predicted/observed ratios of C max and AUC 024 h in rats at different oral doses, with all values falling within the acceptable range of 0.52.0, indicating a well-established PBPK model
[DOI] [PubMed] [Google Scholar] 92.Sharma A., Kaur P., Kumar V., Gill K.D
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