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Overall, ENDS likely confer lower individual health risk compared to continued smoking, but impacts on youth uptake, dual-use, and implications for population health outcomes need ongoing investigation (Sala and Gotti 2023)

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In our present study, tobacco cigarette smoking significantly increased blood pressure in young rats after 12 weeks exposure, while E-cig vaping did not, suggesting that E-cig vaping was less impactful than traditional tobacco smoking