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Kuroda J, Kimura S, Andreeff M , Ashihara E, Kamitsuji Y, Yokota A, Kawata E, Takeuchi M, Tanaka R, Murotani Y, Matsumoto Y, Tanaka H, Strasser A, Taniwaki M, Maekawa T

Researchers are excited about the treatments CagriSema and Tirzepatide for obesity because they represent fresh approaches to weight loss

Wster P, Eriksson I, Vainikka L, llinger K

While GTs initiate extracellular GSH breakdown, the primary intracellular degradation pathway is now thought to be mediated by the cationic transport regulator homolog (ChaC)-like family of -glutamylcyclotransferases (GCT) ( ChaC-like family proteins are remarkably conserved, being found across all phyla from bacteria to humans, where they catalyze intracellular GSH degradation and yield 5-oxoproline and cysteinylglycine (Figure 2)