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Some sources suggest the compound is well-absorbed orally based on rat pharmacokinetic data, while others argue that subcutaneous injection provides more reliable absorption

Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase

Glucose intolerance in Insr P1195L/ +/HFD mice was confirmed by oral glucose tolerance test (OGTT) (Fig