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This reduces endogenous cholesterol levels, which in turn upregulates LDL receptors on the cell surface of hepatocytes, resulting in the removal of circulating cholesterol in the blood (Young and Fong, 2012)

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Psoriasis treat to target: defining outcomes in psoriasis using data from a real-world, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR)