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In the initial study, biomarkers were not able to be monitored, so the strength of these results relied solely on ASD evaluation scales (ABC and SRS) scored by caregivers and by the highly trained medical staff conducting the study

Table 43 Levels of sub-visible particles in the co-formulation containing different concentration ratios of cagrilintide and semaglutide Results for number of sub-visible particles are the mean of 3 replicates and has been rounded to nearest integer value Concluding Remarks The results presented in tables 43 show that after 21 days, virtually no increase in sub-visible particle count was seen in co-formulation 46-60 containing 3.2 mg/ml cagrilintide and up to 12 mg/ml semaglutide

Ideal levels are between 6-9 umol/L of homocysteine

Flanagan, I