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Ultimately, the test of any animal model is its ability to provide new insights into the pathophysiology of the modeled disorder that can be validated in affected patients and, ultimately, may lead to new therapeutic or preventative approaches

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Renal cell death can be mediated by drug transporters that determine the selectivity for the tubular cell, mitochondrial damage, and drug metabolism (Barnett and Cummings 2018)

N-Acetyl-L-Cysteine protects airway epithelial cells during respiratory syncytial virus infection against mucin synthesis, oxidative stress, and inflammatory response and inhibits HSPA6 expression