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Toxicol Sci

Furthermore, they could show that cells lacking both SLC25A39 as well as its paralogue SLC25A40 exhibit defects in the activity and stability of proteins containing ironsulfur clusters (ISCs)

27 Inflammation Obesity associated with overnutrition induces macrophage infiltration and chronic hypoxia, causing low-grade inflammation in the adipose tissue 28 and the release of proinflammatory factors such as interleukin (IL)-1 and tumor necrosis factor (TNF-), 29,30 thus impairing insulin signaling pathway in a number of ways

COL1-related overlap disorder: a novel connective tissue disorder incorporating the osteogenesis imperfecta/EhlersDanlos syndrome overlap