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Description

The schedule mirrors the clinical-trial protocols that drove substantial weight loss around 20% of body weight over 72 weeks on the 15 mg dose [2] while holding gastrointestinal effects down through gradual escalation [1] [4]

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Bone and connective-tissue support during growth Collagen makes up a meaningful share of bone as the flexible scaffold that holds minerals in place

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When a trial is warranted, we use a methylation-aware approach: start low and titrate, define stop/go criteria, and monitor sleep and behavior

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