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You can also have swollen lymph nodes with: Common colds and the flu Sinus infections or sinusitis Minor skin infections Bacterial infections like strep and staph Other causes of swollen lymph nodes Less commonly, swollen lymph nodes can happen with serious conditions like: Viral diseases such as hepatitis, chickenpox and shingles, or measles and rubella Uncommon bacterial diseases like plague or tuberculosis Autoimmune diseases like rheumatoid arthritis, lupus or Sjgrens syndrome Endocrine conditions like hyperthyroidism Reactions to medications like allopurinol (Alloprim or Zyloprim), carbamazepine (Carbatrol, Equetro, Tegretol), hydralazine (Apresoline)or phenytoin (Dilantin) Blood cancers or metastatic cancers Sexually transmitted infections Care and Treatment How are swollen lymph nodes treated