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CAR-ap-enriched CAR19-T cells demonstrate comparable antitumor activity to those enriched using antibodies ( 2.4 Bispecific aptamer The development of a bi-specific aptamer (Bi-apt) platform for cancer therapeutics is formed by two monomeric aptamers, which can specifically bind to two kinds of targets simultaneously with high affinity ( 2.5 Aptamers in combination therapy Aptamers versatility allows for their integration into combination therapies, enhancing their therapeutic potential (40)

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This overlap with the mTOR axis places MOTS-c in an interesting relationship with The Rapamycin Protocol, the most direct pharmaceutical intervention on the mTOR pathway

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