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Supplied as a research peptide, sermorelin is intended exclusively for qualified laboratory and educational research use

The experimental protocol was approved by IACUC of the University of Kentucky based on the NIH guidelines

Definitive diagnosis is made by examination of liver biopsy specimens, with ancillary diagnostics providing supportive information

We therefore introduced linear NHEJ substrates (Supplementary Dataset 1) into transformed mouse embryo fibroblasts (MEFs), under conditions where head-to-tail joining of substrate ends saturates at physiologically relevant levels (tens of repair products/cell) in a physiologically relevant amount of time (tens of minutes) (e.g., Fig