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In TCM theory, hair loss is frequently associated with specific pathological patterns, including kidney deficiency, blood deficiency, dampness-heat, and liver qi stagnation. TCM approaches aim to improve the hair follicle microenvironment and promote hair regrowth by nourishing the liver and kidney, promoting blood flow, eliminating blood stasis, and addressing imbalances like heat and dampness

For copper peptide research specifically, this study demonstrates that delivering copper peptides directly to the follicle (bypassing the skin barrier through microneedling) produces significantly stronger results than topical application alone

Results The area under the time concentration curve (AUC 0-t ) was lower after SC (398 155 ng/mL/min) than IM (696 168 ng/mL/min, p 6 ng/mL for 4 h, with a t of 233 min [10]