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PSE can inhibit the release of inflammatory factors interleukin-1 (IL-1), IL-6, and tumor necrosis factor- (TNF-), and regulate intestinal flora, suggesting that PSE may exert an antidepressant effect through multiple mechanisms [26]

That does not mean they do nothing

A petrolatum or antibacterial ointment and dressing will be applied to the area, which should be kept clean as directed with continued application of ointment

9 Best vitamin C sources: Citrus fruits like oranges and grapefruits Bell peppers and broccoli Strawberries and kiwi fruit Brussels sprouts and cauliflower Fresh herbs like parsley and cilantro For consistent support, consider a high-quality vitamin C supplement