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17 Current Therapeutic Strategies and Limitations Current treatment strategies for OA include non-pharmacological interventions, pharmacological therapies, intra-articular injections (eg, hyaluronic acid, corticosteroids, stem cells), and emerging molecular therapies such as gene editing and exosome-based treatments

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Three baboons received PBS containing a mixture of dKLAK-z13 (100 g ml 1 ) and HLAH-z13 (25 g ml 1 ) in 150 ml through a laparoscope into the peritoneum

108 In March 2015, the FDA required a black box warning on Tanzeum due to the observed risk of thyroid C-cell tumors in animals, although it is unclear if this effect also occurs in humans