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The drug administration methods were intraperitoneal (i.p.) injection 60 min before the formalin injection

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A particular importance for disturbance of mitochondrial function and thereby energy metabolism has been suggested by several studies using biochemical measurements and magnetic resonance (MR) spectroscopy to analyze energy metabolites, including high-energy phosphate levels

Once reconstituted, researchers can explore its effects in cell cultures, biochemical assays, and other laboratory models that investigate cellular responses and signaling behavior