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Excessive excitatory neurotransmitter glutamate is released in the synaptic cleft, glutamate receptors are over-activated, and Ca 2+ flows into neurons, triggering ion homeostasis imbalance, oxidative stress, and mitochondrial dysfunction

Retatrutide has emerged as one of the most effective new weight loss medications, demonstrating potential weight loss of up to 24% after 11 months

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Significantly impairing the quality of life for those affected, the prevalence of hyperuricemia is an upward trend globally, especially in most developed countries