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B12 supplementation may alter gene expression in Cutibacterium acnes bacteria, increasing porphyrin production that promotes follicular inflammation High-dose B12 (especially intramuscular injections of 1,000 micrograms) appears more likely to trigger acne than dietary intake The effect is relatively uncommon and does not affect most people taking B12 supplements Topical acne treatments (benzoyl peroxide, adapalene combinations) can manage breakouts without discontinuing necessary B12 therapy Never stop prescribed B12 treatment without medical supervision, as untreated deficiency causes serious neurological damage and anaemia Suspected adverse reactions to B12 should be reported through the MHRA Yellow Card scheme Table of Contents Can B12 Vitamins Cause Acne

Vitamin B12 is essential for normal blood formation, cellular metabolism, and neurological function

If you do have decreased kidney function and your doctor recommends methylcobalamin, you may need a much higher dose because its less stable, so be sure to ask them about whats best given your condition

IV magnesium may be used to improve athletic performance and reduce muscle soreness