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This is probably because the body stores many years' worth of B 12 in the liver and gastric surgery patients are adequately supplemented with the vitamin
Its clinical application as an antibacterial agent, however, was hampered by the development of allergic reactions (red-man syndrome), bone marrow suppression, vestibular and renal toxicity
Ann Allergy Asthma Immunol 122:263269 Nakatsuji T, Hata TR, Tong Y, Cheng JY, Shafiq F, Butcher AM, Salem SS, Brinton SL, Rudman Spergel AK, Johnson K (2021) Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial
Specifically, fluconazole treatment led to a 20% decrease in GSH levels in Candida albicans ATCC 10231, Candida albicans which are fluconazole-sensitive strains, Candida tropicalis , and Candida metapsilosis
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