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It has been suggested to promote organized collagen formation, enhance fibroblast activity (cells crucial for connective tissue repair), and improve the mechanical strength of repaired tissues

Therefore, the lack of changes in the activity of this enzyme even after very intense aerobic exercise lasting only a dozen or so minutes in our study is a normal reaction, which indirectly indicates the lack or slight reduction of carbohydrate resources in this period 63

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GLS1 levels reportedly increase following mTOR inhibition 57,58 , and we have previously proposed the combination of a GLS inhibitor and aspirin, an mTOR inhibitor, for the treatment of PIK3CA -MT colorectal cancer