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Cell death was assessed using propidium iodide (PI) red fluorescent probe to quantify the proportion of PI-positive cells, as previously reported 53

You may be advised on hydration, monitoring how you feel, and what to do if you notice any unexpected reaction

In the UK, self-administration of hydroxocobalamin injections is supported by the NHS following appropriate training and medical supervision

Moreover, CB-839 has been demonstrated to inhibit myeloma cell proliferation and enhance sensitivity to histone deacetylase (HDAC) inhibitors, suggesting that CB-839 has potential as a therapeutic agent for patients with MM [141]