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Additional contributing factors include increased expression of insulin-like growth factor 1 (IGF1) receptors, IGF1-binding protein (which protects IGF1 from proteolysis) in Purkinje cells [8], as well as upregulated mRNA expression of GLUT1 and GLUT3 [80]

In addition to biological activity as an essential intracellular antioxidant, GSH facilitates the clearance of metabolic waste via GSH- S -transferases and may function as a neuropeptide

Additionally, the results of docking studies disclosed the interaction of GSH with YliB through hydrophobic interaction, polar interaction and charged interaction (Fig

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