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Diese freien Radikale entstehen durch verschiedene Prozesse im Krper und knnen, wenn sie nicht neutralisiert werden, zu erheblichen Schden fhren

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However, in pathological states associated with tinnitus and neurodegeneration, this translocation is impaired or the binding affinity of Nrf2 to ARE is diminished, resulting in insufficient upregulation of antioxidant enzymes (Scuto et al., 2020