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As illustrated in Figure 3, pro-inflammatory cytokines, including TNF-, IL-1, and IL-6, promote OA progression by activating signaling intermediates such as p38 and ERK1/2, leading to upregulation of matrix metalloproteinases (MMPs) and degradation of cartilage structure

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This difference changes how each product is typically handled in research environments

In our article, we explain how stem cells may act in the body after they are administered and what biological processes they are thought to influence