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Clinical CagriSema protocol: Cagrilintide 2.4 mg + Semaglutide 2.4 mg Weekly SC, fixed combination in a single injector 16-week titration from 0.25/0.25 mg to 2.4/2.4 mg For research replication: Molequa offers both peptides separately , you can reconstitute and administer them individually
Products are stored in industrial-grade freezers prior to shipment to maintain stability and purity
A practical compromise involves starting with every-other-day dosing and adjusting based on your response
Topical Administration (Most Common) The most widely used approach is topical application via DMSO (dimethyl sulfoxide): Dissolve 3-5mg Dihexa in a few drops of DMSO Apply to forearm skin (DMSO acts as a carrier to drive the peptide through the skin) DMSO concentration: ~20-30% in the solution Pros: Effective absorption, avoids injection Cons: DMSO has a strong garlic-like odor that can transfer to breath/skin Starting Dose Begin at 1-3mg topically to assess response Work up to 3-5mg if tolerating well Cycling Protocol Dihexa appears to have lasting effects that persist after stopping likely due to synaptogenesis (new connections don't disappear when you stop)
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