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Activation of Sirtuin Pathways (SIRT1) Sirtuins are a family of proteins that regulate metabolism, inflammation, and cellular aging

Photosensitizers (PSs) and light stimuli with a certain wavelength that coincides with the absorption spectra of PSs make up the core of the PDT mechanism

Vitamin B12 (cobalamin) is a water-soluble vitamin essential for neurological function, DNA synthesis, and red blood cell formation

The mechanism involves stimulating over 300 different genes associated with tissue repair and remodeling, fibroblast activation and collagen synthesis, epidermal basal stem cell viability, an anti-inflammatory effect, an antioxidant effect and stimulation of microvascular growth