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IGF-1 DES was originally researched for medical uses, including: Muscle wasting diseases Cachexia Injury rehabilitation Recovery from surgery Support in aging-related muscle loss The goal was to harness IGF-1s anabolic and regenerative potential while reducing systemic effects and controlling the location of its action

Studies have shown that c-MYC , a multifaceted transcriptional factor, upregulates glutamine importers and GLS1 expression and that p53, a tumor-suppressor gene/protein, upregulates GLS2 expression [46,47,48]

Warnings/Contraindication

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