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MOTS-c: The Mitochondrial-Derived Peptide (MDP) One of the most exciting developments in bioenergetics is the discovery of MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)

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Methods: Blood samples were obtained from acute ischemic stroke patients (n = 58) and an age matched control group (n = 20) and were analyzed by microarray technique (miRCURY LNA microRNA Array, Exiqon A/S, Denmark) using a quantitative PCR (qPCR) platform containing 372 miRNA primers

This accuracy makes them especially attractive in stem cell and peptide treatment, where peptides complement the broader activity of MSCs