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The results of cross-sectional studies of subclinical vascular disease show that higher homocysteine concentrations are associated with greater carotid artery intimal-medial wall thickness (Malinow et al, 1993

The product is designed to support normal cellular activity while complementing natural functions

More studies and case reports are necessary to ascertain long-term unknown harms and side-effects

PATHOPHYSIOLOGY AND MECHANISMS Migraine is a complex and disabling neurological disorder, more prevalent in women, whose pathophysiology involves neurovascular mechanisms, mitochondrial dysfunction, neurogenic inflammation, and oxidative stress