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While it was originally studied for human use, its now being explored in veterinary medicine for its regenerative properties in dogs

229,230 The leading response of astrocytes to infectious agents is reactive astrogliosis, which erects parenchymal barriers and encapsulates brain abscesses, thus preventing infection spread

Survival advantage associated with metformin usage in patients with colorectal cancer (CRC) and type II noninsulin-dependent diabetes (NIDDM) 29, 2011