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LONP1 overexpression mitigates hepatocyte mitochondrial dysfunction by restoring the expression and activity of key gluconeogenic enzymes such as glucose 6-phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase 1 (PCK1), whereas LONP1 knockdown exacerbates gluconeogenic impairment and subsequent liver injury [116]

Bacterial lipopolysaccharide increases serotonin metabolism in both medial prefrontal cortex and nucleus accumbens in male wild type rats, but not in serotonin transporter knockout rats

ROS fluorescence intensity, the percentage of ROS-positive area, and the ROS-positive cell rate were compared among the three groups

Recently, our laboratory showed that schisandrin B suppressed colon cancer growth by inducing cell cycle arrest and apoptosis in vitro and in vivo [84]