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on the other hand, they can activate lipid oxidation pathways such as AMP-activated protein kinase and carnitine palmitoyltransferase 1 in the liver, and inhibit lipid synthesis key factors such as fatty acid synthase and sterol regulatory element-binding protein 2, thereby reducing systemic lipid levels in the host, decreasing adiposity, and ameliorating hepatic steatosis [169]

It is worth noting, however, that the risk is lower after gastric banding than after procedures with a malabsorptive component, such as Roux-en-Y gastric bypass or sleeve gastrectomy, because LAGB does not bypass or remove any part of the digestive tract